BACKGROUND: Chronic hepatitis B (CHB) remains a major global health problem. Functional cure is defined as sustained hepatitis B surface antigen (HBsAg) seroclearance with undetectable HBV DNA 24 w...
<p><strong>Tác giả:</strong> Karen Cheuk-Ying Ho, Rex Wan‐Hin Hui, Lung‐Yi Mak, Man‐Fung Yuen</p>
<p>BACKGROUND: Chronic hepatitis B (CHB) remains a major global health problem. Functional cure is defined as sustained hepatitis B surface antigen (HBsAg) seroclearance with undetectable HBV DNA 24 weeks after cessation of therapy. It has emerged as a clinically meaningful endpoint, associated with regression of liver fibrosis, reduced hepatocellular carcinoma (HCC) risk, and a lower treatment burden. However, current CHB therapies, including nucleos(t)ide analogues (NUCs) and pegylated interfe...</p>
<p>📄 DOI: <a href="https://doi.org/https://doi.org/10.1111/jgh.70847" target="_blank" rel="noopener">https://doi.org/10.1111/jgh.70847</a></p>
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