Introduction Granulosa cells are essential regulators of follicular development and oocyte competence, yet the effects of dynamic gonadotropin exposure on granulosa cell function and extracellular...
<p><strong>Tác giả:</strong> Kathryn M. Storey, Ahmed Yehia Gad, Mindy A. Meyers, Heloísa Coppini de Lima, Dawit Tesfaye, Nucharin Songsasen, Jennifer Beth Nagashima</p>
<p>Introduction Granulosa cells are essential regulators of follicular development and oocyte competence, yet the effects of dynamic gonadotropin exposure on granulosa cell function and extracellular vesicle (EV)-mediated communication remain poorly understood. This study aimed to develop a microfluidic platform that more closely mimics in vivo gonadotropin patterns of natural estrus and ovulation stimulation induction cycles, and investigated domestic cat granulosa cell responses under these co...</p>
<p>📄 DOI: <a href="https://doi.org/https://doi.org/10.3389/fcell.2026.1903837" target="_blank" rel="noopener">https://doi.org/10.3389/fcell.2026.1903837</a></p>
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