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Mitochondrial dysfunction in asthma: damage signals sustain airway inflammation and remodeling

26/10/2026 · Thành viên: PGS.TS Nguyễn Chấn Hùng · Nguồn: OpenAlex

Asthma is a heterogeneous disease characterized by chronic airway inflammation and airway remodeling. Growing evidence suggests that mitochondrial dysfunction is not only a consequence of inflammat...

<p><strong>Tác giả:</strong> Yuqian Zhang, Lujia Liu, Mengdi Shi, Yiqiao Li, Suning Mu, Yan Wang, Youpeng Wang</p>

<p>Asthma is a heterogeneous disease characterized by chronic airway inflammation and airway remodeling. Growing evidence suggests that mitochondrial dysfunction is not only a consequence of inflammatory injury but may also contribute to disease persistence and progression. In asthma, mitochondrial redox balance, energy metabolism, Ca 2+ homeostasis, dynamics, biogenesis, and quality control can all become dysregulated. These abnormalities are interconnected and can alter mitochondrial energy su...</p>

<p>📄 DOI: <a href="https://doi.org/https://doi.org/10.3389/fimmu.2026.1883589" target="_blank" rel="noopener">https://doi.org/10.3389/fimmu.2026.1883589</a></p>

<p>📖 <a href="https://doi.org/https://doi.org/10.3389/fimmu.2026.1883589" target="_blank" rel="noopener">Xem bài báo đầy đủ</a></p>

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